The University of Colorado Anschutz (CU Anschutz) has established a collaborative partnership with multiple universities in the U.S., designating itself as a premier study site for visits. This strategic alliance brings together the research expertise of all institutions, fostering a dedicated environment for the investigation and understanding of CADASIL. Through joint efforts, CU Anschutz and the entire Consortium of sites aim to advance knowledge and contribute to the broader scientific community’s understanding of this rare and complex condition.

Karen Orjuela

Position title: Site Principal Investigator


Dr. Orjuela received her MD from the Universidad Nacional de Colombia and her MS from the Medical University of South Carolina. She completed a fellowship in vascular neurology at Loyola University Medical Center. She has received recognition for her excellence in teaching and works as the Co-Director of Diversity Equity, and Inclusion.

Elizabeth Penziner


Elizabeth Penziner is a Research Program Manager in the Department of Neurology at the University of Wisconsin–Madison. She has degrees in Health Promotion and Public Health and has been involved in genetic research throughout her career. Her work, under Dr. Paulsen’s direction in Huntington’s Disease at the University of Iowa, has been published and presented internationally. Current projects include PREVENT-HD and CADASIL, studies of Huntington’s Disease and vascular dementia.

Ryan Morgan

Position title: Clinical Research Coordinator


Ryan Morgan is a research coordinator at the University of Denver in Colorado. She recently graduated from Colorado State University with a bachelor’s degree in Behavioral and Cognitive Neuroscience. She has always been fascinated with the brain and is so grateful to be able to learn more about it in her position as a neurological researcher. Outside work, her favorite hobbies include hiking, playing volleyball, spending time with friends, and watching Netflix with her dog!